GenScript Protein A MagBeads MX are super paramagnetic beads of average 50 μm in diameter, covalently coated with recombinant Protein A. The beads are supplied as 25% slurry in 20% ethanol. The Protein A MagBeads MX have a binding capacity of more than 30 mg human IgG per 1 ml settled beads.

Protein A, a bacterial cell wall protein isolated from Staphylococcus aureus, binds to mammalian IgGs, mainly through Fc regions. Native Protein A has five IgG binding domains and many unknown-function repeated sequences. Recombinant Protein A only contains five high-affinity IgG binding domains to reduce nonspecific binding.

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